Anti-tuberculosis Compounds from Mallotus philippinensis
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چکیده
منابع مشابه
Mallotus philippinensis Muell. Arg (Euphorbiaceae): Ethnopharmacology and Phytochemistry Review
Mallotus philippinensis Muell. Arg (Euphorbiaceae) are widely distributed perennial shrub or small tree in tropical and subtropical region in outer Himalayas regions with an altitude below 1,000 m and are reported to have wide range of pharmacological activities. Mallotus philippinensis species are known to contain different natural compounds, mainly phenols, diterpenoids, steroids, flavonoids,...
متن کاملAntidiabetic Effect of Mallotus Philippinensis in Streptozotocin Induced Diabetic Rats
In the present work the antidiabetic activity of the Mallotus philippinensis was evaluated. The hydroethanolic bark extract showed significant increase in the levels of body weight, insulin and significant decrease in blood glucose, and glycosylated haemoglobin when administered orally for 30 days to STZ induced diabetic rats at a dose of 200 and 400mg/kg body weight. Phytochemical studies also...
متن کاملAntioxidant Activity of Phenolic Fractions of Mallotus philippinensis Bark Extract
Arfan M., Amin H., Karamać M., Kosińska A., Wiczkowski W., Amarowicz R. (2009): Antioxidant activity of phenolic fractions of Mallotus philippinensis bark extract. Czech J. Food Sci., 27: 109–117. Phenolic compounds were extracted from Mallotus philippinensis bark using methanol. Six fractions (I–VI) were separated from the extract on a Sephadex LH-20 column using ethanol and acetone-water as t...
متن کاملNovel Anti-tuberculosis Compounds
The interaction between the mycobacterial thioredoxin reductase (TrxR) and its substrate thioredoxin (Trx) is a promising new drug target for the treatment of tuberculosis, since Mtb lacks the common glutathione system and the mycobacterial TrxR shows a substantial difference in sequence, mechanism and structure to human TrxRs. It was shown that TrxR is essential for thiol redox homeostasis and...
متن کاملPharmacological evaluation of Mallotus philippinensis (Lam.) Muell.-Arg. fruit hair extract for anti-inflammatory, analgesic and hypnotic activity.
OBJECTIVE Recently, we observed wound healing activity of 50% ethanol extract of Mallotus philippinensis Muell. Arg (MP) fruit hairs extract (MPE). In several intestinal infections, localized inflammation is of common occurrence and hence we evaluated the anti-inflammatory, analgesic and hypnotic activity of MPE in different rat experimental models. MATERIALS AND METHODS Anti-inflammatory act...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2010
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1000500208